Selank 10mg

Description

Selank started as tuftsin. The parent peptide is four residues (Thr-Lys-Pro-Arg) and degrades in plasma within minutes, which makes it difficult to study outside short in vitro windows. Adding a Pro-Gly-Pro tail produces Selank, a heptapeptide stable enough to use in rodent behavioural paradigms. Most of the work on it is Russian.

Proposed Mechanism

The behavioural literature describes anxiolytic-like effects in rodent models, but the mechanism does not match a benzodiazepine’s. No binding to the GABA-A receptor has been observed in the available assays. Instead, the working model involves GABAergic and serotonergic modulation indirectly, with a contribution from enkephalin degradation. Kozlovskii et al. (2002) and Semenova et al. (2007) established the behavioural phenotype; the mechanistic question is still open.

Research Literature

The bulk of the Selank literature appears in Russian-language journals from the Institute of Molecular Genetics. English-language reviews are available through Medvedev et al. (2015) and Zozulia et al. (2008), which cover BDNF expression changes and peptide stability. Kolomin et al. (2013, Current Drug Metabolism) is the most recent review in English and covers hippocampal gene expression effects. Human pharmacokinetic data from Russian clinical trials exists but has not been widely replicated in Western literature.

Further reading: PubMed references for this compound.

Research Applications

Used in anxiolytic-like behavioural research, GABAergic signaling studies without direct GABA-A binding, enkephalin degradation assays, and BDNF expression research. Pharmacologically distinct from benzodiazepines.

Supplied strictly for laboratory research use. Not for human or veterinary use.

Reconstitution

Supplied as a lyophilized powder. Reconstitute with bacteriostatic water prior to use. Use the Peptigo reconstitution calculator for guidance on volume and concentration.

Storage

• Unopened: room temperature up to 30 days during transit; refrigerate at 2-8°C long-term.
• Reconstituted: refrigerate at 2-8°C; stable 4-6 weeks. Protect from light.

Quality Verification

Every batch is independently tested by Janoshik Analytical. Certificates of Analysis include HPLC-UV purity, LC-MS identity confirmation, LAL bacterial endotoxin quantification, and USP <71> sterility testing.

Not a drug, supplement, or cosmetic. For in vitro research use only. Not for human consumption.

Frequently Asked Questions

Is this product legal to purchase in Canada for research use?

Peptigo supplies all products strictly for laboratory and in vitro research use. The compound is not a drug, supplement, or cosmetic, and is not sold for human or veterinary use. Researchers purchasing for their own laboratory work, university research programs, or independent in vitro protocols are the intended customer base. Health Canada’s April 2026 advisory specifically addresses unauthorized injectable peptide use; the research-use framing of this product is independent of that consumer-use category.

How is purity verified, and where can I see the Certificate of Analysis?

Every batch is tested independently by Janoshik Analytical, an accredited third-party laboratory. The standard testing panel includes HPLC-UV purity verification, LC-MS identity confirmation, LAL bacterial endotoxin quantification, and USP sterility testing. The Certificate of Analysis for each batch is available on the product page after purchase, and the testing methodology is detailed on the Lab Testing reference page.

What is the standard reconstitution and storage protocol for laboratory use?

The compound is supplied as a lyophilized powder. The standard diluent for reconstitution in research protocols is bacteriostatic water (0.9% benzyl alcohol). The Peptigo reconstitution calculator handles the volume-and-concentration arithmetic for a given target research dose. Unopened lyophilized peptide is stable at room temperature for up to 30 days during transit and should be refrigerated at 2-8°C for long-term storage. Reconstituted peptide should be refrigerated at 2-8°C and is typically functional for 4-6 weeks; protect from light.

Frequently Asked Questions

What is Selank?

Selank is a synthetic peptide derived from the natural peptide tuftsin. In research it is studied for effects on stress-related behavior and cognition in animal models, often discussed alongside its relative Semax.

Selank vs Semax, what’s the difference?

Both are Russian-developed research peptides studied for neurological pathways, but they derive from different parent molecules and are investigated for overlapping but distinct effects. They are frequently studied as a pair.

Is Selank legal in Canada?

Selank is sold as a research material only and is not an approved drug in Canada. Our legality guide covers the details.

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