HGH Kit — 100IU (10 vials × 10IU)

Description

Kit contents: 10 sealed vials × 10IU each (100IU total per kit). Each vial is individually lyophilized and reconstituted independently.

Recombinant human growth hormone is somatropin — 191 amino acids, two disulfide bonds, a four-helix bundle — and sequence-identical to native pituitary GH. Everything useful about it in structural biology comes from that sequence identity. Everything sensitive about it in regulatory terms comes from the same place. This compound is supplied strictly for in vitro receptor biology and structural work.

Proposed Mechanism

The receptor is GHR, a type I cytokine receptor. One GH molecule dimerizes two GHR molecules, activating JAK2-STAT5 signaling and driving IGF-1 transcription in hepatic and peripheral tissues. The dimerization geometry is well-characterized: de Vos et al. (1992, Science) solved the crystal structure of GH bound to the extracellular GHR domain and established the 1:2 ligand-receptor stoichiometry. Cunningham and Wells (1989, 1991) characterized the binding kinetics at sub-nanomolar affinity.

Research Literature

de Vos et al. (1992) is the landmark structural paper. Cunningham and Wells (1989) is the binding characterization. Clackson and Wells (1995) mapped the functional hot spots on the binding interface through alanine-scanning mutagenesis, which is still the reference for researchers asking what parts of the interface actually matter. Waters and Brooks (2015) reviewed the JAK2-STAT5 signaling pathway downstream. This compound has one of the deepest structural-biology literatures of any peptide hormone.

Further reading: PubMed references for this compound.

Research Applications

Used in GHR receptor binding studies, JAK2-STAT5 signaling research, IGF-1 transcriptional regulation assays, and crystal-structure reference applications. One of the most extensively studied peptide hormones in structural biology.

Supplied strictly for laboratory research use. Not for human or veterinary use.

Reconstitution

Supplied as a lyophilized powder. Reconstitute with bacteriostatic water prior to use. Use the Peptigo reconstitution calculator for guidance on volume and concentration.

Storage

• Unopened: room temperature up to 30 days during transit; refrigerate at 2-8°C long-term.
• Reconstituted: refrigerate at 2-8°C; stable 4-6 weeks. Protect from light.

Quality Verification

Every batch is independently tested by Janoshik Analytical. Certificates of Analysis include HPLC-UV purity, LC-MS identity confirmation, LAL bacterial endotoxin quantification, and USP <71> sterility testing.

Not a drug, supplement, or cosmetic. For in vitro research use only. Not for human consumption.

Frequently Asked Questions

Is this product legal to purchase in Canada for research use?

Peptigo supplies all products strictly for laboratory and in vitro research use. The compound is not a drug, supplement, or cosmetic, and is not sold for human or veterinary use. Researchers purchasing for their own laboratory work, university research programs, or independent in vitro protocols are the intended customer base. Health Canada’s April 2026 advisory specifically addresses unauthorized injectable peptide use; the research-use framing of this product is independent of that consumer-use category.

How is purity verified, and where can I see the Certificate of Analysis?

Every batch is tested independently by Janoshik Analytical, an accredited third-party laboratory. The standard testing panel includes HPLC-UV purity verification, LC-MS identity confirmation, LAL bacterial endotoxin quantification, and USP sterility testing. The Certificate of Analysis for each batch is available on the product page after purchase, and the testing methodology is detailed on the Lab Testing reference page.

What is the standard reconstitution and storage protocol for laboratory use?

The compound is supplied as a lyophilized powder. The standard diluent for reconstitution in research protocols is bacteriostatic water (0.9% benzyl alcohol). The Peptigo reconstitution calculator handles the volume-and-concentration arithmetic for a given target research dose. Unopened lyophilized peptide is stable at room temperature for up to 30 days during transit and should be refrigerated at 2-8°C for long-term storage. Reconstituted peptide should be refrigerated at 2-8°C and is typically functional for 4-6 weeks; protect from light.